Fig. 5.

Iso-surface contour plots of the 3-D image reconstructions based on measurements from both Side A and Side B of phantom (i.e. X-Y plane and Z-Y plane of phantom) and guided using a priori information obtained from 2D surface imaging were presented in the X-Y and X-Z planes, using 1% Liposyn phantom under perfect uptake conditions for Study III. The a priori information for each experimental case was obtained using cut-off value of 80% and 10:1 target to background contrast values. A single 0.45 cc target was located at (a) [1.5, 2.5, 2] cm, (b) [2, 2.5, 2] cm, (c) [2.5, 2.5, 2] cm, (d) [2, 2.5, 2.5] cm, and (e) [2.5, 2.5, 2.5] cm. The solid sphere in each plot represents the true target location and the irregular solid region represents the reconstructed target location. A cut-off value (selected based on the first break point of histogram plot of μ_axf) was applied to iso-surface contour plots in order to differentiate the target from the background. Only 4 cm along the depth is presented in the plot, although the total depth, Z=10 cm for Side A and X=10cm for Side B of the phantom.