TABLE 3.

Effect of chronic intake of sweetened water and bile acids on mRNA expression

	Water	Water + Bile Acids	Fructose	Fructose + Bile Acids
Occludin	3.1 ± 0.5	1.7 ± 0.3a	2.4 ± 0.2	1.4 ± 0.3a
Xbp1	7.7 ± 1.0	2.3 ± 0.5a	10.5 ± 2.0bd	4.1 ± 1.2
Xbp1s	7.1 ± 0.7	2.3 ± 0.7ac	9.7 ± 1.5	5.8 ± 1.6

Feeding of fructose-sweetened water and bile acids is described in Material and Methods. Data are means ± SEM (n = 6). XBP1, X-box binding protein 1; XBP1s, spliced X-box binding protein 1.

^aP < 0.05 compared with mice fed water.

^bP < 0.05 compared with mice fed water enriched with bile acids.

^cP < 0.05 compared with mice fed with 30% fructose solution.

^dP < 0.05 compared with mice fed fructose solution enriched with bile acids.