Fig. 3.

Comparison of effects of dalcetrapib and torcetrapib. A: Using clone 6/2 as capture antibody. B: Using clone JHC-1 as capture antibody. Data shown in A and B are the mean of independent measurements with duplicates using seven individual human plasma samples (n = 14). Error bars represent the SD of all values. C: ELISA using clone 6/2 (circles) and clone JHC-1 (triangles) applied to plasma of volunteers receiving a single oral dose (600 mg) of dalcetrapib. D: Correlation of CETP ELISA and CETP activity. E: Dalcetrapib concentration in plasma of healthy volunteers treated with 600 mg dalcetrapib. Data shown in C, D, and E are the mean ± SEM for n = 22; statistical analysis of ELISA data in Fig. 2C resulted in *P < 0.01 and ***P < 0.0001 (paired Student's t-test).