Fig. 5.
Comparison of the effect of dalcetrapib, torcetrapib, and anacetrapib on HDL-C·AUC and radioactivity of fecal total sterols as a percentage of injected radioactivity in the hamster macrophage reverse cholesterol transport (RCT) study. HDL-C·AUC during the RCT study period was calculated from plasma HDL-C levels (day 0, 3, 7, and 10) by the trapezoidal method. Error bars represent the SD for n = 5 or 6 animals. *P < 0.01 (HDL·AUC); #P < 0.01 (radioactivity of fecal total sterols) vs. control (Dunnett test).