TABLE 4.
Content of apolipoproteins quantified by immunoturbidimetry or ELISA in LDL subfractions
| Apolipoprotein | LDL(+) | LDL(−) | Ratio (−)/(+) | Ratio from LC-ESI MS/MS |
|---|---|---|---|---|
| ApoA-I (mmol/mol apoB) | 68 ± 15 | 233 ± 17a | 3.4 | 3.8 |
| ApoA-II (mmol/mol apoB) | 10 ± 8 | 56 ± 12a | 5.4 | 4.8 |
| ApoE (mmol/mol apoB) | 23 ± 21 | 93 ± 30a | 4.0 | 5.2 |
| ApoC-III (mmol/mol apoB) | 49 ± 27 | 210 ± 145a | 4.3 | 4.2 |
| ApoC-II (mmol/mol apoB) | 33 ± 5 | 43 ± 5 | 1.3 | 1.8 |
| ApoJ (mmol/mol apoB) | 1.6 ± 1.5 | 10.2 ± 8.4 | 6.4 | 11.0 |
All apolipoproteins were quantified by commercial immunoturbidimetric methods as described in “Methods,” except apoJ, which was measured by ELISA. Values are mean ± SD expressed in mmol/mol apoB. Apo, apolipoprotein.
a
P < 0.05 versus LDL(+) using the Wilcoxon t-test.