Table 2.
KCNMB1 variant Glu65Lys: diploid genotype and allele frequencies across four biogeographic ancestry groups (ancestry determined by self-identification)
| Biogeographic ancestry | Individuals n | Chromo-somes (2n) | Glu65Lys diploid genotype |
Allele, A |
HWE p value | |||
|---|---|---|---|---|---|---|---|---|
| Glu/Glu | Glu/Lys | Lys/Lys | Glu65 | 65Lys | ||||
| White | 452 | 904 | 398 | 54 | 0 | 94.0 | 6.0 | 0.177 |
| Black | 342 | 684 | 310 | 32 | 0 | 95.3 | 4.7 | 0.364 |
| Asian | 150 | 300 | 125 | 24 | 1 | 91.3 | 8.7 | 0.896 |
| Hispanic | 120 | 240 | 98 | 20 | 2 | 90.0 | 10.0 | 0.417 |
| Global | 1,064 | 2,128 | 931 | 130 | 3 | 93.6 | 6.4 | 0.490 |
The genotype frequencies differed across populations, χ2 = 18.4, d.f. = 6, p = 0.005.