Fig. 5.

Knockout of EIF2C2 expression decreases cellular proliferation in JHU-012 and expression of EIF2C2 after pooled siRNA transfection. a Pooled transfection of EIF2C2 siRNA decreases cellular proliferation relative to transfected scrambled controls. Each experiment was run in triplicate and repeated independently at least 3 times. Graphs shown are representative. b Quantitative RT-PCR data showing decreased expression of EIF2C2 after pooled siRNA transfection. Expression level is normalized to BETA-ACTIN expression. Error bars correspond to the standard deviation of the average of each sample run in triplicate.