Figure 5. Time spent engaged in escape-oriented behavior during (a) FST and (b) TST.
In the FST, GAP43 (+/−) males displayed significantly decreased active swimming than (+/+) males. This difference was not seen between (+/−) and (+/+) females. GAP43 (+/+) mice displayed sex differences, with (+/+) males spending significantly more time engaged in active swimming than (+/+) females. In the TST, GAP43 (+/−) mice displayed significantly decreased struggling compared to (+/+) mice. There were no sex differences in the TST. (*p≤0.05,**p≤0.01)