Skip to main content
. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Control Release. 2010 Aug 19;147(3):400–407. doi: 10.1016/j.jconrel.2010.08.019

Figure 5.

Figure 5

Comparison of in vivo collagen capsule thickness for murine sub-dermal hydrogel-coated implants explanted after two weeks for (a) negative control, no siRNA loaded, (b) 2μg mTOR siRNA loaded, (c) 10μg mTOR siRNA loaded and (d) positive control, 10 μg TGF-β siRNA loaded. Localization of fibrous capsule is marked by white arrows (scale bar = 100μm). (e) Summary of collagen capsule thickness data. P values for each individual group vs. negative control without siRNA treatment are: 0.3112 (2μg mTOR siRNA), 0.3954 (10μg mTOR siRNA), and 0.7045 (10μg TGF-β siRNA).