Table 5.

Univariate and Bivariate Odds Ratio (P-value) for An Association of Oral contraceptives, Estrogen Alone, and Progestin With or Without Estrogen With Incident Venous Thromboembolism After Adjusting Individually for Patient Age, Body Mass Index and Previously-Identified Venous Thromboembolism Risk Factors²⁵

Model	Oral Contraceptives	Estrogen Alone	Progestin ± Estrogen
	— OR (95% CI, P-value) —
Age-adjusted only	2.64 (1.52–4.60, <0.001)	1.29 (0.89–1.87, 0.18)	2.02 (1.36–2.99, <0.001)
Body mass index (kg/m2)	2.59 (1.47–4.57, 0.001)	1.36 (0.93–1.99, 0.11)	2.30 (1.53–3.45, <0.001)
Hospitalization, with or without surgery	3.22 (1.70–6.13, <0.001)	1.33 (0.85–2.09, 0.21)	2.08 (1.33–3.27, 0.002)
Nursing home confinement	2.64 (1.52–4.60, <0.001)	1.31 (0.90–1.91, 0.16)	2.07 (1.39–3.07, <0.001)
Trauma/fracture	2.56 (1.46–4.47, 0.001)	1.34 (0.91–1.96, 0.14)	2.16 (1.43–3.26, <0.001)
Active cancer	2.97 (1.66–5.32, <0.001)	1.52 (1.01–2.28, 0.04)	1.72 (1.12–2.65, 0.013)
Neurologic Disease w/Leg paresis	3.01 (1.69–5.35, <0.001)	1.27 (0.87–1.85, 0.21)	1.98 (1.33–2.95, <0.001)
Varicose veins	2.63 (1.51–4.58, <0.001)	1.27 (0.88–1.85, 0.20)	2.02 (1.36–2.99, <0.001)
Pregnancy or postpartum	3.45 (1.87–6.34, <0.001)	1.27 (0.87–1.84, 0.21)	2.00 (1.35–2.97, <0.001)