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. Author manuscript; available in PMC: 2011 Sep 22.
Published in final edited form as: Biochim Biophys Acta. 2010 Sep 22;1799(9):622–629. doi: 10.1016/j.bbagrm.2010.09.003

Figure 5. Dominant negative Per1 inhibits αENaC promoter activity.

Figure 5

mpkCCDc14 cells were transfected with pRL renilla luciferase and a plasmid containing the αENaC promoter cloned in front of the firefly luciferase cDNA. Cells were co-transfected with empty vector or dominant negative Per1 (dnPer1) expression vector and then treated with vehicle or 1 μM aldosterone for 24 hr. Data are presented as the mean ± standard error, n=3, *p<0.05 versus αENaC/luc + vector + vehicle; † p<0.05 versus αENaC/luc + vector + aldosterone