Fig. 6.
Pulmonary responses after viral challenge. (A) Lung virus titer and (B) lung cytokine IL-6. Lung samples from individual mice in each group (n=4) were collected on day 4 after challenge with a lethal dose of mouse-adapted A/PR/8/34. Each lung sample was diluted to 1 ml with DMEM medium to determine lung virus titers and cytokine IL-6. Groups of mice are as described in the legend of Fig. 2. ANOVA showed no significant differences among groups MN(H), IM(H) and MN(L). A significant difference was found between groups MN(L) and IM(L) (p<0.01).