Table 1.
Patient, clinical, disease, and transplant characteristics of patients before and after HCT
| a) Demographic and clinical factors at time of transplant | ||
|---|---|---|
| Variable | N | Distribution (%) |
| Patient Factors | ||
| Age | 662 | |
| Mean (SD), years | 42.1 (11) | |
| Median (range), years | 42.4 (18, 71) | |
| < 35 | 182 | 28% |
| 35–39 | 95 | 14% |
| 40–44 | 106 | 16% |
| 45–49 | 120 | 18% |
| >50 | 159 | 24% |
| Gender | ||
| Male | 411 | 62% |
| Female | 251 | 38% |
| Race | ||
| White | 603 | 92% |
| Other | 56 | 8% |
| Marital status | 655 | |
| Married/living with partner/committed | 493 | 75.3 |
| Other | 162 | 24.7 |
| Clinical Factors | ||
| Comorbid conditions (dichotomized as present or not) |
104 | 16% |
| Malignant disease at initial diagnosis, n (%) | ||
| Acute leukemia (AML or ALL) | ||
| Chronic leukemia (CML) | 243 | 37% |
| Breast cancer | 131 | 20% |
| Lymphoma (Hodgkin’s disease or non- Hodgkin’s lymphoma) |
156 | 24% |
| 132 | 20% | |
| Intensity of treatment before HCT | ||
| Less intense | 441 | 66.6 |
| More intense | 221 | 33.4 |
| Type of transplant | ||
| Allogeneic | 272 | 41.1 |
| Autologous | 390 | 58.9 |
| TBI in transplant conditioning regimen | 235 | 35.5 |
| b) Demographic and clinical factors after transplant at time of QOL interview | ||
|---|---|---|
| Variable | N | Distribution (%) |
| Patient Factors | ||
| Education | 658 | |
| High school or below | 194 | 30 |
| Some college or technical education | 209 | 32 |
| College degree (BA/BS) | 122 | 18 |
| Education beyond bachelor’s degree | 133 | 20 |
| Marital status | 659 | |
| Married/living with partner/committed | 483 | 73 |
| Other | 176 | 27 |
| Occupational status | ||
| Retired | 75 | 11 |
| Not working | 100 | 15 |
| Working or student | 484 | 73 |
| Family income | ||
| <$20,000 | 70 | 11 |
| $20,000–40,000 | 141 | 22 |
| $40,000–60,000 | 156 | 24 |
| $60,000–80,000 | 100 | 15 |
| >$80,000 | 181 | 28 |
| Insurance status | 597 | |
| Public | 193 | 32 |
| Private | 387 | 65 |
| No insurance | 17 | 3 |
| Clinical Factors | ||
| Comorbid conditions | 104 | 16% |
| Severity of transplant experience | ||
| Low severity (autologous) | 390 | 60 |
| Intermediate severity (allogeneic without chronic GVHD) |
168 | 26 |
| High severity (allogeneic with chronic GVHD) | 88 | 14 |
| Time since transplant, in years, median, (standard deviation) (mean) |
662 | 6.6 (3.1) (7.0) |
| Distance between transplant center and residence (in miles) (standard deviation) |
600 | 148 (317) |
Acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), total body irradiation (TBI)