Table 2.
Demographic and treatment characteristics of acute lymphoblastic leukemia (ALL) survivors stratified by hematopoietic cell transplantation (HCT) status.
| Characteristic | Non-HCT n=48 |
HCT n=26 |
P-value |
|---|---|---|---|
| Site, n (%) | |||
| Seattle, WA | 30 (62.5) | 21 (80.8) | 0.12 |
| Nashville, TN | 18 (37.5) | 5 (19.2) | |
| Female, n (%) | 26 (54.2) | 10 (38.5) | 0.23 |
| Non-white race/ethnicity | 10 (20.8) | 8 (30.8) | 0.40 |
| Median current age (range), yrs | 14 (8–21) | 15 (8–21) | 0.36 |
| Median years (range) since diagnosis | 10 (3–18) | 10.5 (1–15) | 0.83 |
| Median years (range) since HCT | - | 6 (1–13) | - |
| History of relapse, n (%)1 | - | 16 (61.5) | - |
| Radiation exposure, n (%) | |||
| Cranial radiotherapy | 5 (10.4) | 10 (38.5) | 0.007 |
| Total body irradiation | - | 26 (100) | - |
| History of chronic graft vs. host disease, n (%) | - | 16 (61.5) | - |
1
Eligibility for the non-HCT cohort was restricted to those in first complete remission. Ten HCT patients were transplanted in first complete remission due to very high risk disease per institutional practice.