Table 3.
Metabolic parameters of ALL survivors, stratified by HCT status.
| Outcomes | Non-HCT n=48 |
HCT n=26 |
P-value |
|---|---|---|---|
| Height z-score, mean (±SD) | 0.30 ± 0.99 | −0.59 ± 1.19 | <0.01 |
| BMI z-score, mean (±SD) | 0.80 ± 0.92 | 0.54 ± 1.29 | 0.31 |
| BMI ≥25 or ≥85th percentile for age & sex, n (%) | 19 (39.6) | 11 (42.3) | 1.00 |
| BMI ≥30 or ≥95th percentile for age & sex, n (%) | 13 (27.1) | 6 (23.1) | 0.79 |
| Waist ≥90th percentile for age & sex1, n (%) | 13 (27.1) | 7 (26.9) | 1.00 |
| Waist-hip ratio, mean (±SD) | 0.83 (0.07) | 0.90 (0.06) | <0.01 |
| Blood pressure ≥120/80 or ≥90th percentile for age & height, n (%) | 8 (16.7) | 11 (42.3) | 0.03 |
| Glucose, median (range), mg/dL | 82 (43–96) | 82 (63–110) | 0.76 |
| Insulin, median (range), mU/L | 6.5 (1.0, 26.9) | 11.7 (1.0, 39.6) | <0.01 |
| HOMA-IR, median (range) | 1.32 (0.11, 5.51) | 2.64 (0.18, 10.76) | <0.01 |
| Triglycerides, median (range), mg/dL | 63 (16, 177) | 127 (63, 327) | <0.01 |
| HDL, median (range), mg/dL | 54 (33, 108) | 45 (32, 63) | <0.01 |
| Cardiometabolic traits, n (%)2 | |||
| 0 | 24 (50.0) | 4 (15.4) | |
| 1 | 14 (29.2) | 8 (30.8) | Overall |
| 2 | 8 (16.7) | 8 (30.8) | <0.01 |
| ≥3 | 2 (4.2) | 6 (23.1) |
HOMA-IR: homeostasis model assessment of insulin resistance
1
Or if waist circumference ≥80 cm (females), ≥94 cm (males).
2
As defined by the Consensus criteria (Table 1).