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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Behav Brain Res. 2010 Aug 19;216(1):332–340. doi: 10.1016/j.bbr.2010.08.013

Figure 3.

Figure 3

A. Immunolabeling for neurofibrillary tangle antigen in CA1 stratum lacunosum moleculare entorhinal terminal field. The absence of labeling in stratum radiatum is indicative of control sections processed without primary antibody. B. Immunolabeling for neurofibrillary tangle tau in entorhinal cortex: Small (1) and large (2) neurons exhibited perikaryal NFT tau, in close proximity to other neurons (3) that showed no labeling. A few strongly immunoreactive objects smaller than neurons resembled ghost tangles (4; cf. Ikeda, Haga, Oyanagi, Iritani, and Kosaka, 1992). Other small densely labeled objects may be glia (6) but some are too small and are more likely to be degenerated neuronal processes (5, 7). C. Argentophilic Gallyas staining in similar field to A. D. Gallyas staining in entorhinal cortex shows several NFT along with smaller degeneration detritus. Scale bars = 50 μm in A, C, D and 25 μm in B.