Table 2.
Mean relative CRH, CRH-R1, BDNF, NGF, NT3, trkB, and trkA mRNA expression levels
| Probe/Brain Region | Controls | Increased Complexity |
Exercise |
|---|---|---|---|
| CRH | |||
| PVN | 200 (15) | 277 (13) | 244 (19) |
| CRH R1 | |||
| MeA | 33 (6) | 39 (7) | 43(9) |
| BDNF | |||
| BLA* | 18 (3) | 19 (3) | 35 (7)ab |
| Dentate Gyrus* | 157 (28) | 242 (27)a | 498 (52)ab |
| CA1* | 35 (10) | 27 (9)a | 7 (2)a |
| CA3* | 95 (13) | 164 (18)a | 298 (37)ab |
| V. Hipp./ Sub. zone* | 16(2) | 18 (3) | 27 (3)a |
| NGF | |||
| Dentate Gyrus* | 47 (5) | 42 (5) | 68 (6)ab |
| CA1 # | 5 (1) | 7(1)a | 7(1)a |
| CA3 | 5 (1) | 6 (1) | 8 (1) |
| NT3 | |||
| Dentate Gyrus | 57 (6) | 49 (5) | 49 (4) |
| trkB | |||
| Dentate Gyrus | 92 (5) | 89 (7) | 98 (6) |
| CA1 | 55 (2) | 54 (3) | 59 (4) |
| CA3 | 31 (3) | 30 (3) | 32 (4) |
| trkA | |||
| CA1 | 6 (1) | 5 (1) | 5 (2) |
| CA3 | 11 (3) | 19 (5) | 17 (5) |
Mean relative CRH, CRH-R1, BDNF, NGF, NT3, trkB, and trkA mRNA expression levels (mean integrated grey values/100 +/− 1 SEM; presented as arbitrary units) measured in several brain regions from control, increased complexity, and exercise rats immediately following final (day 11) noise stress.
significant one way ANOVA, p < 0.05.
indicates a difference from controls,
indicates a significant difference from increased complexity animals, Tukey HSD, p < 0.05.
independent samples t-test in which X and IC values were grouped together, p < 0.05. (MeA- medial amygdala; BLA-basolateral amygdala; v. hipp- ventral hippocampus; sub. zone- subicular zone; PVN-paraventricular nucleus of the hypothalamus).