Table 2.
Patient, Disease, and Transplant Characteristics of Caucasian Patients with MDS or CML
| MDS | CML | |
|---|---|---|
| Number of patients | 765 | 1644 |
| Age (years) median (range) | 48.3 (0.9 – 78.9) | 37.1 (0.7 – 69.7) |
| Patient-donor gender (No. of pts. [%]): | ||
| Female-Female | 150 (20) | 307 (19) |
| Female-Male | 168 (22) | 343 (21) |
| Male-Female | 186 (24) | 401 (24) |
| Male-Male | 253 (33) | 588 (36) |
| Unknown | 8 (1) | 5 (<1) |
| Conditioning Regimen (No. of pts [%])1: | ||
| High intensity | 706 (92) | 1626 (99) |
| Reduced-intensity | 59 (8) | 18 (1) |
| Donor (No. of pts. [%]): | ||
| HLA-identical sibling | 346 (45) | 731 (44) |
| HLA-matched unrelated donor | 349 (46) | 676 (41) |
| Non-sibling relative or mismatched sibling | 62 (8) | 235 (14) |
| Autologous* | 8 (1) | 2 (<1) |
| Stem Cell Source (No. of pts. [%]): | ||
| Bone marrow | 403 (53) | 1522 (93) |
| Peripheral blood | 356 (47) | 117 (7) |
| Bone marrow+peripheral blood | 4 (<1) | 2 (<1) |
| Cord blood | 2 (<1) | 3 (<1) |
| Years transplanted (No. of pts. [%]): | ||
| 1969–1985 | 26 (3) | 228 (14) |
| 1986–1990 | 75 (10) | 391 (24) |
| 1991–1995 | 162 (21) | 490 (30) |
| 1996–2000 | 173 (23) | 393 (24) |
| 2001–2005 | 224 (29) | 113 (7) |
| 2006-present | 105 (14) | 29 (2) |