Table 1.
Clinical characteristics of the study population
| Characteristics | European-Americans (n=304) | African-Americans (n=224) | P-value |
|---|---|---|---|
| Men/Women | 195/109 | 126/98 | NS |
| Metabolic syndrome (%) | 199 (65%) | 110 (49%) | <0.001 |
| Coronary artery disease (%) | 173 (57%) | 99 (44%) | 0.003 |
| Diabetes mellitus (%) | 63 (21%) | 66 (29%) | 0.018 |
| Age (years) | 56.6 ± 0.6 | 54.8 ± 0.6 | 0.023 |
| Systolic blood pressure (mm Hg) | 125 ± 1.0 | 129 ± 2.0 | NS |
| Diastolic blood pressure (mm Hg) | 75 ± 0.6 | 79 ± 1.4 | 0.005 |
| Waist circumference (cm) | 105 ± 1.0 | 96 ± 1.1 | <0.001 |
| Total cholesterol (mg/dl) | 197 ± 2.3 | 198 ± 3.0 | NS |
| LDL cholesterol (mg/dl) | 123 ± 2.0 | 126 ± 2.8 | NS |
| HDL cholesterol (mg/dl) | 41 ± 0.7 | 49 ± 1.1 | <0.001 |
| Triglyceride (mg/dl) | 151 (110–216) | 106 (80–144) | <0.001 |
| Glucose (mg/dl) | 132 ± 3.8 | 119 ± 3.3 | 0.013 |
| Insulin (μU/ml) | 15.1 (9.2–25.2) | 14.1 (8.7–21.7) | NS |
| Apolipoprotein B (mg/dl) | 136 ± 2.0 | 134 ± 2.7 | NS |
| Apolipoprotein A-I (mg/dl) | 122 ± 1.3 | 130 ± 1.9 | <0.001 |
| ApoB/apoA-I | 1.15 ± 0.33 | 1.07 ± 0.37 | 0.008 |
| Composite cardiovascular score | 12.9 (1.9–27.1) | 8.3 (1.5–24.9) | NS |
Values are expressed as mean ± SE and median (interquartile range) for non-normally distributed values. Group means were compared using Student’s t-tests and proportions were compared using χ2 analysis. Values for triglycerides and insulin were logarithmically transformed before analyses. Apo, apolipoprotein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NS, non significant.