Table III.
Within-person differences of cartilage thickness (ThCtAB) in the A–P subregions of the medial femoral condyle (MF) for knees with medial joint space narrowing (mJSN) grade 1 (n = 45), grade 2 (n = 21) and grade 3 (n = 7) compared to contra-lateral knees with JSN grade 0
| Plate | OARSI mJSN grade | Mean difference [μm] | Mean difference [%] | SD difference [μm] | Z-score | P-value (paired t test) | FDR P-value |
|---|---|---|---|---|---|---|---|
| 0–30° | JSN 1 | −100 | −5.5 | 290 | −0.3 | 0.025 | 0.048 |
| JSN 2 | −440 | −24 | 370 | −1.3 | <0.001 | 0.003 | |
| JSN 3 | −970 | −53 | 260 | −2.9 | <0.001 | 0.003 | |
| 15–45° | JSN 1 | −120 | −6.6 | 280 | −0.4 | 0.006 | 0.014 |
| JSN 2 | −450 | −25 | 310 | −1.4 | <0.001 | 0.003 | |
| JSN 3 | −1025 | −56 | 220 | −3.2 | <0.001 | 0.003 | |
| 30–60° | JSN 1 | −140 | −7.5 | 290 | −0.4 | 0.003 | 0.008 |
| JSN 2 | −480 | −26 | 290 | −1.5 | <0.001 | 0.003 | |
| JSN 3 | −1070 | −58 | 190 | −3.3 | <0.001 | 0.003 | |
| 45–75° | JSN 1 | −20 | −8.1 | 320 | −0.5 | 0.002 | 0.006 |
| JSN 2 | −500 | −26 | 320 | −1.5 | <0.001 | 0.003 | |
| JSN 3 | −1080 | −57 | 260 | −3.2 | <0.001 | 0.003 | |
| 60–90° | JSN 1 | −130 | −6.5 | 300 | −0.4 | 0.008 | 0.017 |
| JSN 2 | −380 | −20 | 320 | −1.2 | <0.001 | 0.003 | |
| JSN 3 | −850 | −44 | 420 | −2.6 | 0.002 | 0.006 | |
| 75–105° | JSN 1 | −60 | −2.9 | 260 | −0.2 | 0.170 | 0.249 |
| JSN 2 | −200 | −11 | 340 | −0.6 | 0.015 | 0.030 | |
| JSN 3 | −480 | −25 | 550 | −1.5 | 0.062 | 0.104 | |
| 90–120° | JSN 1 | +10 | +0.3 | 270 | +0.0 | 0.883 | 0.937 |
| JSN 2 | −50 | −2.7 | 340 | −0.2 | 0.511 | 0.598 | |
| JSN 3 | −240 | −13 | 630 | −0.8 | 0.352 | 0.476 | |
| 105–135° | JSN 1 | +30 | +1.8 | 290 | +0.1 | 0.431 | 0.541 |
| JSN 2 | +40 | +2.1 | 290 | +0.1 | 0.543 | 0.614 | |
| JSN 3 | −110 | −5.7 | 680 | −0.3 | 0.695 | 0.761 | |
| 120–150° | JSN 1 | +30 | +1.9 | 260 | +0.1 | 0.388 | 0.496 |
| JSN 2 | −10 | −0.3 | 250 | −0.0 | 0.916 | 0.957 | |
| JSN 3 | +20 | +0.9 | 560 | +0.1 | 0.943 | 0.957 |
SD difference = standard deviation of the differences between mJSN and no-mJSN knees; Z-score = cartilage thickness difference between JSN and no-JSN knees expressed in number of standard deviations of cartilage thickness in the 73 no-JSN knees [for the A–P subregions please see Fig. 2(c)]; negative values imply a smaller cartilage thickness compared with contra-lateral no-JSN knees.