Figure 1.

The crystal structure of TtgV. (A) Ribbon representation of TtgV monomer colored from N termini (blue) to C termini (red). The secondary structural elements are mapped onto the amino acid sequence using the same color scheme as on the right. (B) TtgV tetramer arrangement and interactions. Each monomer is colored differently. Proposed hydrophobic residues that form the effector-binding pocket are displayed as balls and sticks. The insert shows the β5 interactions between trans-dimers. The blue ellipse indicates the cis-dimer, while the orange ellipse indicates the trans-dimer.