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. 2010 Jun 27;65(8):747–752. doi: 10.1136/thx.2009.128504

Figure 1.

Figure 1

Study designs for double-blind single maintenance and reliever therapy (SMART) studies. (A) Comparison of inhaled corticosteroid (ICS) monotherapy with ICS/long-acting β agonist (LABA).15 (B) Comparison of ICS monotherapy with ICS/LABA.16 (C) Comparison of ICS monotherapy with two doses of ICS/LABA, SMART being the higher dosage ICS/LABA treatment arm.17 (D) Comparison of three ICS/LABA treatment arms: with short-acting β2 agonist, with additional LABA or with additional ICS and additional LABA.19 BUD, budesonide; FORM, formoterol.