Table 1.
Frequencies of RBC antibody problems, in 782 liver transplant patients receiving 1000 liver transplants
| Adults (n = 496) | Children (n = 286) | |||||||
|---|---|---|---|---|---|---|---|---|
| Antibody problem* | Before transplant |
After transplant |
Total | Percentage | Before transplant |
After transplant |
Total | Percentage |
| Alloantibodies | 60 | 50 | 110 | 22.2 | 16 | 24 | 40 | 14.0 |
| Significant | 31 | 37 | 68 | 13.7 | 3 | 15 | 18 | 6.3 |
| Insignificant | 42 | 20 | 62 | 12.5 | 13 | 9 | 22 | 7.7 |
| Other† | 0 | 1 | 1 | 0.2 | 1 | 1 | 2 | 0.7 |
| Positive DAT | 44 | 74 | 118 | 23.8 | 5 | 23 | 28 | 9.8 |
| Nonreactive eluate | 25 | 34 | 59 | 11.9 | 4 | 6 | 10 | 3.5 |
| Panreactive eluate | 3 | 1 | 4 | 0.8 | 1 | 0 | 1 | 0.3 |
| No eluate | 14 | 4 | 18 | 3.6 | 0 | 0 | 0 | 0.0 |
| Alloantibody | 1 | 8 | 9 | 1.8 | 0 | 5 | 5 | 1.7 |
| Delayed | 1 | 7 | 8 | 0 | 4 | 4 | ||
| Anti-D in Rh+ | 0 | 1 | 1 | 0 | 1 | 1 | ||
| Graft ABO antibody | 0 | 13 | 13 | 2.6 | 0 | 7 | 7 | 2.4 |
| Passive ABO antibody | 0 | 10 | 10 | 2.0 | 0 | 3 | 3 | 1.0 |
| Other‡ | 1 | 8 | 9 | 1.8 | 0 | 2 | 2 | 0.7 |
| All problems | 99 | 80 | 179 | 36.1 | 20 | 37 | 57 | 19.9 |
*
Patients with multiple problems are counted in each individual category.
†
Anti-D from Rh immune globulin (1 child) or of uncertain transient nature in 2 Rh+ patients who are also included below in DAT alloantibodies.
‡
IgG and C3 (n = 3), C3 (n = 6; 4 adults and both children), or not tested monospecifically (n = 2).