Table 5.
Survival, Causes of Graft Failure, and Liver Function Tests Connected With Results of Arterial Ketone Body Ratio (AKBR) in Patients With or Without PGE1
| Group I | Group II (PGE1) | |||||
|---|---|---|---|---|---|---|
| Range of AKBR | Class 1 AKBR ≥ 1.0 |
Class 2 0.7 ≤ AKBR < 1.0 |
Class 3 AKBR < 0.7 |
Class 1 AKBR ≥ 1.0 |
Class 2 0.7 ≤ AKBR < 1.0 |
Class 3 AKBR < 0.7 |
| Number of primary grafts | 145 | 78 | 15 | 93 | 32 | 9 |
| Graft survival at 1 month | 140 (96.6%) | 63 (80.8%)a | 0 (0%)b | 90 (96.8%) | 31 (96.9%) | 5 (55.6%)c |
| Patient survival at 1 month | 143 (98.6%) | 75 (97.3%) | 12 (80.0%) | 91 (97.8%) | 31 (96.9%) | 9 (100%) |
| Causes of graft failure at 1 month | ||||||
| Primary nonfunction | 0 | 6 | 8 | 0 | 0 | 1 |
| Primary dysfunction | 0 | 2 | 0 | 0 | 0 | 0 |
| HAT, HA stricture. and/or PVT | 1 | 3 | 7 | 0 | 0 | 3 |
| Other technical | 0 | 1 | 0 | 0 | 0 | 0 |
| Rejection | 0 | 0 | 0 | 0 | 0 | 0 |
| Cardiac problems including pulmonary hypertension | 2 | 0 | 0 | 1 | 0 | 0 |
| Infection or sepsis | 2 | 1 | 0 | 2 | 1 | 0 |
| Encephalopathy. brain death | 0 | 2 | 0 | 0 | 0 | 0 |
| Peak AST (IU/L) | 1607 ± 13 | 2852 ± 44d,* | 5836 ± 352#+ | 1800 ± 18 | 2868 ± 94 | 6439 ± 457e,#+ |
| Rise in AST for the first 24 h (IU/L) | 1128 ± 45 | 212 ± 78f,* | 2275 ± 615# | 868 ± 14 | 108 ± 98 | 649 ± 313 |
| Peak PT (sec) | 16.8 ± 0.03 | 20.2 ± 0.1g,* | 22.9 ± 1.1# | 16.7 ± 0.03 | 20.1 ± 0.2h,* | 27.2 ± 1.0#+ |
| CIT (h/min) | 13.49 | 13.46 | 14.52 | 14.20 | 14.09 | 13.53 |
| Range of CIT (h/min) | 4.08–27.21 | 4.43–27.38 | 11.48–23.07 | 6.37–23.02 | 8.53–20.10 | 10.58–19.06 |
Class 1 vs Class 2 in group I P < .005.
Class 2 vs Class 3 in group I P < .0001.
Class 1 vs Class 3 in group II P < .001: Class 2 vs Class 3 in group II P < .01; Class 3 in group I vs Class 3 in group II P < .01.
Peak AST in group I*: Class 1 vs class 2 P < .01. #; Class 1 vs Class 3 P < .01, +; Class 2 vs Class 3 P < .01.
Peak AST in group II #: Class 1 vs Class 3 P < .01, +; Class 2 vs Class 3 P < .01.
Rise in AST in group I*: Class 1 vs Class 2 P < .05, #; Class 1 vs Class 3 P < .01, +; Class 2 vs Class 3 P < .05.
PT (prothrombin time) in group I*: Class 1 vs Class 2 P < .05, #; Class 1 vs Class 3 P < .01.
PT in group II*: Class I vs Class 2 P < .01, #; Class 1 vs Class 3 P < .01, +; Class 2 vs Class 3 P < .01.
HAT, hepatic arteria: thrombosis; PVT, portal vein thrombosis.