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. 2010 Jul 12;588(Pt 17):3277–3293. doi: 10.1113/jphysiol.2010.192823

Figure 4. Suppression of recombinant homomeric Kv7.4, but not heteromeric Kv1.2/Kv1.5 and Kv2.1/Kv9.3 currents by linopirdine.

Figure 4

A, representative families and mean ±s.e.m. (n= 4) normalized (to peak current at +45 mV in control condition) I–V relations for whole-cell Kv7.4 currents (HEK 293 cells) in the absence (Control) and presence of 1 μm linopirdine. B, representative families and mean ±s.e.m. (n= 3) normalized (to peak current at +45 mV in control condition) I–V relations for whole-cell Kv1.2/Kv1.5 currents (HEK 293 cells) in the absence (Control) and presence of 1 μm linopirdine. C, representative families and mean ±s.e.m. (n= 3) normalized (to peak current at +45 mV in control condition) I–V relations for whole-cell Kv2.1/Kv9.3 currents (HEK 293 cells) in the absence (Control) and presence of 1 μm linopirdine. Note the lack of suppression of Kv1.2/Kv1.5 and Kv2.1/Kv9.3 currents by linopirdine at 1 μm.