Table 2.
Glycoproteins upregulated in skin tumors
| IPI | Protein Name | Protein Location | Ca | Pa | Nr | Total | Ca/Nr | Pa/Nr | Ca/Pa |
|---|---|---|---|---|---|---|---|---|---|
| IPI00119063 | AM2 receptor | Transmembrane | 17 | 0 | 0 | 17 | 100.0 | 100.0 | 100.0 |
| IPI00381122 | Weakly similar to Tiarin | Cell Surface | 11 | 0 | 0 | 11 | 100.0 | 100.0 | 100.0 |
| IPI00308971 | Cation-independent mannose-6-phosphate receptor | Transmembrane | 8 | 0 | 0 | 8 | 100.0 | 100.0 | 100.0 |
| IPI00124265 | Latent transforming growth factor beta binding protein 4 | Secreted | 7 | 0 | 0 | 7 | 100.0 | 100.0 | 100.0 |
| IPI00129304 | Collectin sub-family member 12 | Transmembrane | 7 | 0 | 0 | 7 | 100.0 | 100.0 | 100.0 |
| IPI00129968 | Embigin | Transmembrane | 7 | 0 | 0 | 7 | 100.0 | 100.0 | 100.0 |
| IPI00153959 | Stabilin-1 | Transmembrane | 5 | 0 | 0 | 5 | 100.0 | 100.0 | 100.0 |
| IPI00316575 | Cathepsin K | Cell Surface | 4 | 0 | 0 | 4 | 100.0 | 100.0 | 100.0 |
| IPI00321190 | Sulfated glycoprotein 1 | Secreted | 4 | 0 | 0 | 4 | 100.0 | 100.0 | 100.0 |
| IPI00475154 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa | Transmembrane | 4 | 0 | 0 | 4 | 100.0 | 100.0 | 100.0 |
| IPI00308785 | Prostaglandin G/H synthase 2 | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00122737 | 222 kDa protein | Intracellular | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00406459 | Arylsulfatase B | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00409393 | Latent transforming growth factor beta binding protein, isoform 1L | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00119809 | Mama protein | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00111960 | Lysosomal alpha-glucosidase | Transmembrane | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00118011 | Mannosidase, beta A, lysosomal | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00121120 | Procollagen, type V, alpha 2 | Secreted | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00129158 | Tyrosine-protein phosphatase non-receptor type substrate 1 | Transmembrane | 3 | 0 | 0 | 3 | 100.0 | 100.0 | 100.0 |
| IPI00120769 | Solute carrier family 29 (nucleoside transporters), member 1 | Transmembrane | 5 | 0 | 1 | 6 | 5.0 | 0.0 | 100.0 |
| IPI00415773 | Integrin alpha-M | Transmembrane | 34 | 3 | 1 | 38 | 34.0 | 3.0 | 11.3 |
| IPI00338785 | CDNA, clone:M5C1012G13 product:laminin B1 subunit 1 | Intracellular | 9 | 1 | 3 | 13 | 3.0 | 0.3 | 9.0 |
| IPI00130627 | Legumain | Secreted | 17 | 2 | 0 | 19 | 100.0 | 100.0 | 8.5 |
| IPI00113480 | Myeloperoxidase | Secreted | 8 | 1 | 0 | 9 | 100.0 | 100.0 | 8.0 |
| IPI00113824 | Basement membrane-specific heparan sulfate proteoglycan core protein | Cell Surface | 15 | 2 | 5 | 22 | 3.0 | 0.4 | 7.5 |
| IPI00124830 | Leukocyte surface antigen CD47 | Transmembrane | 7 | 1 | 1 | 9 | 7.0 | 1.0 | 7.0 |
| IPI00320605 | Integrin beta-2 | Transmembrane | 20 | 3 | 0 | 23 | 100.0 | 100.0 | 6.7 |
| IPI00308990 | Monocyte differentiation antigen CD14 | Cell Surface | 13 | 2 | 0 | 15 | 100.0 | 100.0 | 6.5 |
| IPI00133082 | CD177 antigen | Secreted | 6 | 1 | 0 | 7 | 100.0 | 100.0 | 6.0 |
| IPI00130486 | FK506-binding protein 9 | Cell Surface | 5 | 1 | 0 | 6 | 100.0 | 100.0 | 5.0 |
| IPI00308609 | VESICULAR INTEGRAL-MEMBRANE PROTEIN VIP36 | Transmembrane | 5 | 1 | 0 | 6 | 100.0 | 100.0 | 5.0 |
| IPI00403938 | Tenascin C | Cell Surface | 133 | 29 | 0 | 162 | 100.0 | 100.0 | 4.6 |
| IPI00462199 | Basigin | Transmembrane | 13 | 3 | 0 | 16 | 100.0 | 100.0 | 4.3 |
| IPI00120245 | Integrin alpha-V | Transmembrane | 8 | 2 | 0 | 10 | 100.0 | 100.0 | 4.0 |
| IPI00120245 | Integrin alpha-V | Transmembrane | 8 | 2 | 0 | 10 | 100.0 | 100.0 | 4.0 |
| IPI00110852 | Translocon-associated protein alpha, muscle specific isoform | Cell Surface | 4 | 1 | 0 | 5 | 100.0 | 100.0 | 4.0 |
| IPI00125266 | Acid ceramidase | Secreted | 4 | 1 | 0 | 5 | 100.0 | 100.0 | 4.0 |
| IPI00121038 | Versican core protein | Cell Surface | 11 | 3 | 2 | 16 | 5.5 | 1.5 | 3.7 |
| IPI00124283 | Macrophage scavenger receptor types I and II | Transmembrane | 7 | 2 | 0 | 9 | 100.0 | 100.0 | 3.5 |
| IPI00132067 | Fibulin-2 | Secreted | 31 | 9 | 0 | 40 | 100.0 | 100.0 | 3.4 |
| IPI00223769 | CD44 antigen | Transmembrane | 10 | 3 | 0 | 13 | 100.0 | 100.0 | 3.3 |
| IPI00127447 | Lysosome membrane protein II | Transmembrane | 32 | 10 | 0 | 42 | 100.0 | 100.0 | 3.2 |
| IPI00322447 | RA175 | Transmembrane | 6 | 2 | 0 | 8 | 100.0 | 100.0 | 3.0 |
| IPI00154057 | Protocadherin 1 | Cell Surface | 3 | 1 | 0 | 4 | 100.0 | 100.0 | 3.0 |
| IPI00121312 | MFIRE1 | Secreted | 3 | 1 | 0 | 4 | 100.0 | 100.0 | 3.0 |
| IPI00124640 | Osteoclast-like cell cDNA, clone:I420031M06 product:granulin | Secreted | 3 | 1 | 0 | 4 | 100.0 | 100.0 | 3.0 |
| IPI00134483 | Lectin lambda | Cell Surface | 3 | 1 | 1 | 5 | 3.0 | 1.0 | 3.0 |
| IPI00272381 | Proline 4-hydroxylase, alpha 1 | Secreted | 17 | 6 | 0 | 23 | 100.0 | 100.0 | 2.8 |
| IPI00122493 | FK506-binding protein 10 | Secreted | 7 | 3 | 0 | 10 | 100.0 | 100.0 | 2.3 |
| IPI00123831 | SDR1 protein | Transmembrane | 11 | 5 | 0 | 16 | 100.0 | 100.0 | 2.2 |
| IPI00224728 | Cd63 antigen | Transmembrane | 8 | 4 | 0 | 12 | 100.0 | 100.0 | 2.0 |
| IPI00128689 | Collagen alpha 1(V) chain | Secreted | 6 | 3 | 0 | 9 | 100.0 | 100.0 | 2.0 |
| IPI00125877 | Hypothetical protein | Transmembrane | 6 | 3 | 0 | 9 | 100.0 | 100.0 | 2.0 |
| IPI00130015 | Dipeptidyl-peptidase I | Secreted | 4 | 2 | 0 | 6 | 100.0 | 100.0 | 2.0 |
| IPI00318012 | T-cell immunomodulatory protein | Transmembrane | 4 | 2 | 0 | 6 | 100.0 | 100.0 | 2.0 |
| IPI00123678 | Cadherin-22 | Transmembrane | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00126316 | Mast cell carboxypeptidase A | Secreted | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00130661 | Tripeptidyl-peptidase I | Cell Surface | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00131366 | Keratin, type II cytoskeletal 6B | Transmembrane | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00221418 | hypothetical Phospholipase D/Transphosphatidylase | Transmembrane | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00279051 | RIKEN cDNA A930025J12 | Transmembrane | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00554833 | Eosinophil-associated ribonuclease 12 | Secreted | 2 | 1 | 0 | 3 | 100.0 | 100.0 | 2.0 |
| IPI00127280 | Myeloid bactenecin | Secreted | 43 | 22 | 0 | 65 | 100.0 | 100.0 | 2.0 |
| IPI00118413 | Thrombospondin 1 | Secreted | 20 | 11 | 0 | 31 | 100.0 | 100.0 | 1.8 |
| IPI00127352 | AMBP protein | Secreted | 22 | 14 | 0 | 36 | 100.0 | 100.0 | 1.6 |
| IPI00132600 | Niemann-Pick C1 protein | Transmembrane | 3 | 2 | 0 | 5 | 100.0 | 100.0 | 1.5 |
| IPI00137177 | Lysosomal protective protein | Secreted | 3 | 2 | 0 | 5 | 100.0 | 100.0 | 1.5 |
| IPI00132474 | Integrin beta-1 | Transmembrane | 18 | 13 | 1 | 32 | 18.0 | 13.0 | 1.4 |
| IPI00123342 | Hypoxia up-regulated 1 | Secreted | 19 | 14 | 0 | 33 | 100.0 | 100.0 | 1.4 |
| IPI00126090 | Integrin alpha-3 | Transmembrane | 4 | 3 | 0 | 7 | 100.0 | 100.0 | 1.3 |
| IPI00131881 | ADAM 10 | Cell Surface | 4 | 3 | 0 | 7 | 100.0 | 100.0 | 1.3 |
| IPI00406434 | Mini-agrin | Secreted | 4 | 3 | 0 | 7 | 100.0 | 100.0 | 1.3 |
| IPI00410951 | Thyroxine-binding globulin homolog | Secreted | 4 | 3 | 0 | 7 | 100.0 | 100.0 | 1.3 |
| IPI00125058 | Laminin alpha-3 chain | Secreted | 9 | 7 | 1 | 17 | 9.0 | 7.0 | 1.3 |
| IPI00112326 | Epithelial membrane protein 1 | Transmembrane | 6 | 5 | 0 | 11 | 100.0 | 100.0 | 1.2 |
| IPI00128154 | Cathepsin L | Secreted | 23 | 20 | 0 | 43 | 100.0 | 100.0 | 1.2 |
| IPI00121362 | F11r protein | Transmembrane | 9 | 9 | 0 | 18 | 100.0 | 100.0 | 1.0 |
| IPI00108535 | Carcinoembryonic antigen-related cell adhesion molecule 1 | Cell Surface | 7 | 7 | 0 | 14 | 100.0 | 100.0 | 1.0 |
| IPI00407222 | PREDICTED: similar to human KIAA1815 protein | Transmembrane | 6 | 6 | 0 | 12 | 100.0 | 100.0 | 1.0 |
| IPI00128989 | Vacuolar ATP synthase subunit S1 | Transmembrane | 5 | 5 | 0 | 10 | 100.0 | 100.0 | 1.0 |
| IPI00471081 | RIKEN cDNA 1100001H23 | Cell Surface | 5 | 5 | 0 | 10 | 100.0 | 100.0 | 1.0 |
| IPI00226932 | Quinoprotein alcohol dehydrogenase structure containing protein | Secreted | 4 | 4 | 0 | 8 | 100.0 | 100.0 | 1.0 |
| IPI00127672 | PREDICTED: hypothetical protein LOC66967 | Secreted | 2 | 2 | 0 | 4 | 100.0 | 100.0 | 1.0 |
| IPI00346978 | Spink5 protein | Secreted | 2 | 2 | 0 | 4 | 100.0 | 100.0 | 1.0 |
| IPI00469387 | GUGU alpha | Secreted | 23 | 23 | 3 | 49 | 7.7 | 7.7 | 1.0 |
| IPI00134549 | Lysosome-associated membrane glycoprotein 2 | Transmembrane | 8 | 9 | 0 | 17 | 100.0 | 100.0 | 0.9 |
| IPI00121430 | Collagen alpha 1(XII) chain | Secreted | 11 | 14 | 0 | 25 | 100.0 | 100.0 | 0.8 |
| IPI00122272 | Extracellular matrix protein 1 | Secreted | 11 | 14 | 0 | 25 | 100.0 | 100.0 | 0.8 |
| IPI00227969 | Integrin alpha-6 | Transmembrane | 6 | 8 | 1 | 15 | 6.0 | 8.0 | 0.8 |
| IPI00134652 | Type VII collagen | Secreted | 5 | 7 | 0 | 12 | 100.0 | 100.0 | 0.7 |
| IPI00114256 | Synaptophysin-like protein | Transmembrane | 10 | 14 | 3 | 27 | 3.3 | 4.7 | 0.7 |
| IPI00110810 | Prostate stem cell antigen | Secreted | 9 | 13 | 0 | 22 | 100.0 | 100.0 | 0.7 |
| IPI00467180 | Translocon-associated protein beta subunit | Transmembrane | 15 | 22 | 0 | 37 | 100.0 | 100.0 | 0.7 |
| IPI00133172 | Serpin B11 | Intracellular | 2 | 3 | 0 | 5 | 100.0 | 100.0 | 0.7 |
| IPI00111013 | Cathepsin D | Secreted | 19 | 30 | 0 | 49 | 100.0 | 100.0 | 0.6 |
| IPI00117093 | Laminin beta-3 chain | Cell Surface | 3 | 6 | 0 | 9 | 100.0 | 100.0 | 0.5 |
| IPI00130342 | Lymphocyte antigen 6 complex locus G6C protein | Secreted | 2 | 4 | 0 | 6 | 100.0 | 100.0 | 0.5 |
| IPI00125293 | Eosinophil cationic protein 1 | Secreted | 1 | 2 | 0 | 3 | 100.0 | 100.0 | 0.5 |
| IPI00320204 | RIKEN cDNA 2210023G05 | Secreted | 1 | 2 | 0 | 3 | 100.0 | 100.0 | 0.5 |
| IPI00468097 | 340 kDa protein | Secreted | 4 | 8 | 1 | 13 | 4.0 | 8.0 | 0.5 |
| IPI00113853 | Desmocollin-3 | Transmembrane | 2 | 6 | 0 | 8 | 100.0 | 100.0 | 0.3 |
| IPI00319814 | Suprabasal-specific protein suprabasin | Secreted | 3 | 10 | 0 | 13 | 100.0 | 100.0 | 0.3 |
| IPI00115854 | TROP2 protein | Transmembrane | 1 | 4 | 0 | 5 | 100.0 | 100.0 | 0.3 |
| IPI00127933 | Androgen binding protein alpha | Secreted | 1 | 4 | 0 | 5 | 100.0 | 100.0 | 0.3 |
| IPI00130249 | GPI-anchored metastasis-associated protein homolog | Secreted | 10 | 60 | 0 | 70 | 100.0 | 100.0 | 0.2 |
| IPI00111014 | Elongation of very long chain fatty acids protein 4 | Transmembrane | 3 | 20 | 2 | 25 | 1.5 | 10.0 | 0.2 |
| IPI00129243 | Gamma-glutamyl hydrolase | Secreted | 1 | 8 | 0 | 9 | 100.0 | 100.0 | 0.1 |
| IPI00338790 | Glandular kallikrein KLK13 | Cell Surface | 0 | 6 | 0 | 6 | 0.0 | 100.0 | 0.0 |
| IPI00111115 | Similar to METASTASIS-ASSOCIATED GPI- ANCHORED PROTEIN | Secreted | 0 | 4 | 0 | 4 | 0.0 | 100.0 | 0.0 |
| IPI00473830 | Biliary glycoprotein | Transmembrane | 0 | 4 | 0 | 4 | 0.0 | 100.0 | 0.0 |
| IPI00153548 | Hypothetical protein | Transmembrane | 0 | 3 | 0 | 3 | 0.0 | 100.0 | 0.0 |
Ca/Nr: Ratio of spectral count of carcinomas to normal tissue
Pa/Nr: Ratio of spectral count of apillomas to normal tissue
Ca/Pa: Ratio of spectral count of carcinomas to papillomas