Table 3.
Odds ratio (95% CI) for newly diagnosed diabetes corresponding to a one-standard deviation increase in continuous variables stratified by waist circumference categories. Only the variables entered into the final logistic regression model are presented.
| Standard deviation | FPG ≥7.0 mmol/L and/or 2hPG ≥11.1 mmol/L OR (95% CI) |
HbA1c ≥6.5% OR (95% CI) | HbA1c ≥5.6%* OR (95% CI) |
|
|---|---|---|---|---|
| Men | ||||
|
| ||||
| Waist circumference <90 (cm) ( n = 671) | ||||
|
| ||||
| Age (year) | 10.41 | 1.46 (1.12,1.89) | — | — |
| Positive family history of diabetes | — | 3.04 (1.60,5.77) | — | — |
| Gamma-glutamyltransferase (U/L) | 0.72 | 1.59 (1.29,1.96) | — | — |
| Systolic blood pressure (mmHg) | 19.25 | 1.38 (1.08,1.76) | — | 1.30 (1.10,1.53) |
| Total cholesterol (mmol/L) | 1.03 | — | 1.32(1.04,1.66) | — |
| School years >9 (≤9) | — | — | 0.59(0.34,0.98) | — |
|
| ||||
| Waist circumference ≥90 (cm) ( n = 496) | ||||
|
| ||||
| Age (year) | 10.41 | 1.62 (1.21,2.19) | — | — |
| Positive family history of diabetes | — | 2.42 (1.28,4.58) | — | — |
| Low-density lipoprotein cholesterol (mmol/L) | 0.97 | 1.61 (1.23,2.10) | — | 1.61 (1.28,2.02) |
| Triglyceride (mmol/L) | 1.10 | 1.64 (1.26,2.14) | — | — |
| School years >9 (≤9) | — | — | 0.46 (0.25,0.85) | — |
| Body mass index (kg/m2) | 2.52 | — | 1.50 (1.05,2.15) | 1.27 (1.01,1.60) |
| Smoking | — | — | 2.29 (1.24,4.22) | — |
|
| ||||
| All ( n = 1167) | ||||
|
| ||||
| Age (year) | 10.41 | 1.65 (1.37,1.99) | — | — |
| Positive family history of diabetes | — | 2.35 (1.50,3.66) | — | — |
| Gamma-glutamyltransferase (U/L) | 0.72 | 1.42 (1.18,1.72) | — | — |
| Low-density lipoprotein cholesterol (mmol/L) | 0.97 | 1.26 (1.06,1.49) | — | 1.32 (1.17,1.49) |
| Triglyceride (mmol/L) | 1.10 | 1.30 (1.11,1.52) | — | — |
| School years >9 (≤9) | — | — | 0.50 (0.34,0.74) | — |
| Total cholesterol (mmol/L) | 1.03 | — | 1.24 (1.04,1.47) | — |
|
| ||||
| Women | ||||
|
| ||||
| Waist circumference <80 (cm) ( n = 667) | ||||
|
| ||||
| Age (year) | 9.74 | 1.75 (1.26, 2.44) | — | — |
| Positive family history of diabetes | — | 2.42 (1.12,5.21) | — | — |
| Gamma-glutamyltransferase (U/L) | 0.54 | 1.83 (1.32,2.54) | — | — |
| School years >9 (versus ≤9) | — | — | 0.31 (0.15,0.64) | — |
| Systolic blood pressure (mmHg) | 22.42 | — | — | 1.34 (1.09,1.64) |
|
| ||||
| Waist circumference ≥80 (cm) ( n = 940) | ||||
|
| ||||
| Age (year) | 9.74 | 1.47 (1.19,1.82) | — | 1.19 (1.04,1.36) |
| C-reactive protein | 1.02 | 1.30 (1.11,1.51) | — | — |
| Gamma-glutamyltransferase (U/L) | 0.54 | 1.56 (1.27,1.91) | — | — |
| Systolic blood pressure (mmHg) | 22.42 | 1.22 (1.02,1.48) | — | — |
| Triglyceride (mmol/L) | 0.80 | 1.57 (1.30,1.89) | — | — |
| School years >9 (versus ≤9) | — | — | 0.44 (0.26,0.75) | — |
|
| ||||
| All ( n = 1607) | ||||
|
| ||||
| Age (year) | 9.74 | 1.44 (1.19,1.73) | — | 1.15 (1.02,1.28) |
| Positive family history of diabetes | — | 1.66 (1.09,2.51) | — | — |
| Gamma-glutamyltransferase (U/L) | 0.54 | 1.57 (1.31,1.87) | — | — |
| C-reactive protein (mg/dl) | 1.02 | 1.21 (1.00,1.45) | — | — |
| Low-density lipoprotein cholesterol (mmol/L) | 0.92 | 1.22 (1.04,1.43) | — | 1.16 (1.04,1.29) |
| Triglyceride (mmol/L) | 0.80 | 1.48 (1.26,1.74) | — | — |
| Systolic blood pressure (mmHg) | 22.42 | 1.26 (1.06,1.49) | — | 1.30 (1.10,1.53) |
| School years >9 (≤9) | — | — | 0.36 (0.23,0.55) | — |
Age, body mass index, gamma-glutamyltransferase, low-density lipoprotein cholesterol, triglyceride, total cholesterol, C-reactive protein, systolic blood pressure, family history of diabetes, school years, smoking, and alcohol-drinking are fitted in the models.C-reactive protein and gamma-glutamyltransferase were logarithmic transformed. *Optimal cutoff value for diagnosis of diabetes in this study population [16].