Table 3.
eAE on MPO activity.
| Groups | MPO activity (U/mg) days of ulceration | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 7 | |
| Sham treated | 0.0153±0.003 | 0.0143 ± 0.005 | 0.0217 ± 0.003 | 0.021 ± 0.004 | 0.0224 ± 0.004 |
| Ulcerated untreated | 1.1454∗,b,f,g±0.074 | 1.8849∗,b,f,ggg ± 0.061 | 2.7606∗,bb,ff,ggg ± 0.047 | 2.6111∗,bb,ff,gg ± 0.18 | 1.7655∗,bb,ff,g ± 0.164e |
| eAE (120 mg/kg) | 1.2417 ± 0.049 | 1.9407 ± 0.039 | 3.7863 ± 0.334 | 3.783 ± 0.313 | 3.6187 ± 0.042 |
| eAE (100 mg/kg) | 1.0868 ± 0.047 | 1.8523 ± 0.079 | 3.8357 ± 0.049 | 3.77 ± 0.119 | 2.9305 ± 0.036 |
| eAE (80 mg/kg) | 1.0825 ± 0.052 | 1.5424 ± 0.056 | 2.1369 ± 0.097 | 2.0766 ± 0.045 | 1.817 ± 0.045 |
| eAE (70 mg/kg) | 1.0079 ± 0.005 | 1.2408 ± 0.048 | 1.92 ± 0.031 | 1.853 ± 0.033 | 1.166 ± 0.047 |
| eAE (60 mg/kg) | 0.7585aaa,bb ± 0.031 | 1.0599aaa,bb± 0.008 | 1.5363aaa,bb ± 0.027 | 1.45aaa,bb ± 0.053 | 0.8439aaa,bb ± 0.038 |
| eAE (50 mg/kg) | 1.0223aa± 0.006 | 1.6236aaa± 0.017 | 2.3861aa ± 0.009 | 2.3069a ± 0.009 | 1.5302aa ± 0.051 |
| eAE (40 mg/kg) | 1.0623a±0.038 | 1.5827aaa± 0.047 | 2.7629a ± 0.015 | 2.7488a ± 0.036 | 1.8709a ± 0.081 |
| Omeprazole(3 mg/kg) | 1.0285 ± 0.008 | 1.3929 ± 0.009 | 1.9145 ± 0.029 | 1.755 ± 0.062 | 1.0359 ± 0.014 |
The values are mean (n = 8) and (±) indicates S.D. *P < .001 when compared to the Sham Treated; a P > .05, aa P < .05, aaa P < .001 when compared to ulcerated untreated; b P > .05, bb P < .001 whencompared to eAE (120 mg/kg); f P > .05, ff P < .001 when compared to eAE (100 mg/kg); g P > .05, gg P < .05, ggg P < .001 when compared to eAE (80 mg/kg) treated group.