Table 1.
Baseline characteristics of patients above or below the respective cut-off levels for MR grade, LVEF and plasma BNP
| All patients (n=725) |
MR >1/≤1 (n=90/635) |
p Value | LVEF <0.40/≥0.40 (n=110/615) | p Value | BNP >373/≤373 (n=180/545) | p Value | |
| Mean age (years) | 65 | 70/64 | <0.0001 | 70/64 | <0.0001 | 70/63 | <0.0001 |
| Female (%) | 29 | 39/28 | 0.05 | 24/30 | 0.17 | 37/27 | 0.01 |
| History (%) | |||||||
| MI | 20 | 36/18 | 0.0002 | 36/17 | <0.0001 | 29/17 | 0.001 |
| Angina pectoris | 40 | 59/38 | 0.0002 | 43/40 | 0.60 | 47/38 | 0.04 |
| CHF | 8 | 27/5 | <0.0001 | 22/5 | <0.0001 | 17/5 | <0.0001 |
| PCI/CABG | 12 | 21/11 | 0.02 | 16/12 | 0.21 | 15/12 | 0.24 |
| Risk factors (%) | |||||||
| Current smoker | 34 | 27/35 | 0.18 | 38/33 | 0.32 | 30/35 | 0.27 |
| Diabetes mellitus | 18 | 26/17 | 0.04 | 18/18 | 0.89 | 21/17 | 0.26 |
| Hypertension | 40 | 51/39 | 0.03 | 42/40 | 0.75 | 51/37 | 0.0008 |
| Hypercholesterolaemia | 28 | 31/28 | 0.53 | 32/27 | 0.36 | 24/29 | 0.22 |
| GFR <60 ml/min | 38 | 62/35 | <0.0001 | 53/36 | 0.001 | 59/31 | <0.0001 |
| Diagnosis (%) | |||||||
| STEMI | 47 | 43/48 | 0.43 | 49/47 | 0.76 | 46/48 | 0.73 |
| Anterior | 48 | 26/50 | 0.004 | 74/43 | <0.0001 | 57/45 | 0.06 |
| Inferior | 50 | 64/49 | 0.09 | 19/56 | <0.0001 | 39/54 | 0.02 |
| Unspecified | 2 | 10/<1 | 0.004 | 7/1 | 0.01 | 5/1 | 0.06 |
| Non-STEMI | 35 | 43/34 | 0.10 | 39/35 | 0.39 | 46/32 | 0.0006 |
| Unstable angina pectoris | 17 | 13/18 | 0.37 | 12/18 | 0.10 | 8/21 | <0.0001 |
| 10-year mortality (%) | 36.3 | 70.2/31.5 | <0.0001 | 67.5/30.7 | <0.0001 | 56.3/29.4 | <0.0001 |
BNP, brain natriuretic peptide; CABG, coronary artery bypass grafting; CHF, congestive heart failure; GFR, glomerular filtration rate; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MR, mitral regurgitation, PCI, percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.