TABLE 6.
GMCs and proportions of infants achieving putatively protective levels following a fourth dose of PCV7
| Serotype | IgG GMC (95% CI)a |
No. of infants achieving putatively protective levels (%) |
||||||
|---|---|---|---|---|---|---|---|---|
| Postimmunization |
Postbooster |
Postimmunization |
Postbooster |
|||||
| Term (n = 29) | Preterm (n = 32) | Term | Preterm | Term | Preterm | Term | Preterm | |
| 4 | 1.27 (0.88-1.84) | 1.27 (0.88-1.84) | 3.84 (2.72-5.42) | 2.08 (1.47-2.93) | 26 (90) | 24 (75) | 29 (100) | 32 (100) |
| 6B | 0.13 (0.10.0.17) | 0.07 (0.04-0.10) | 5.95 (3.28-10.78) | 2.13 (1.31-3.46) | 3 (10) | 2 (6) | 28 (97) | 31 (97) |
| 9V | 0.81 (0.57-1.16) | 0.52 (0.38-0.72) | 3.60 (2.73-4.75) | 2.29 (1.64-3.21) | 24 (83) | 21 (66) | 29 (100) | 31 (97) |
| 14 | 2.62 (1.70-4.04) | 2.39 (1.57-3.64) | 10.54 (7.88-14.10) | 6.46 (4.32-9.84) | 27 (93) | 29 (91) | 29 (100) | 32 (100) |
| 18C | 1.08 (0.84-1.37) | 0.69 (0.53-0.89) | 1.99 (1.57-2.51) | 1.19 (0.84-1.68) | 28 (97) | 27 (84) | 29 (100) | 29 (91) |
| 19F | 2.09 (1.45-2.99) | 1.05 (0.78-1.42) | 4.51 (3.13-6.51) | 1.83 (1.25-2.70) | 28 (97) | 30 (94) | 29 (100) | 30 (94) |
| 23F | 1.01 (0.65-1.57) | 0.27 (0.16-0.43) | 4.79 (3.11-7.37) | 1.60 (0.95-2.70) | 27 (93) | 17 (53) | 29 (100) | 28 (88) |
| 1 | 0.02 (0.01-0.02) | 0.01 (0.01-0.02) | 0.05 (0.03-0.11) | 0.02 (0.02-0.03) | 0 | 0 | 8 (28) | 0 |
| 5 | 0.07 (0.05-0.10) | 0.03 (0.02-0.04) | 0.29 (0.20-0.43) | 0.08 (0.05-0.13) | 0 | 0 | 15 (52) | 5 (16) |
a
Values shown are in μg/ml.