TABLE 1.
Mean endpoint titers of antibody responses in sera and intestinal lavage fluid of vaccinated and control (PBS or LT R192G) mice (n = 9)
| Immunizing agent(s) | Endpoint titer (range)a |
|||
|---|---|---|---|---|
| Serum |
Intestinal lavage fluid |
|||
| Plates coated with MOMP | Plates coated with GST-PorA | Plates coated with MOMP | Plates coated with GST-PorA | |
| PBS | 0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| LT R192G | 0 (0-0) | 11 (0-100) | 20 (0-100) | 40 (0-100) |
| GST-PorA + LT R192G | 1,444 (200-3,200)* | 1,956 (800-3,200)* | 2,667 (800-3,200)†‡ | 3,200 (3,200-3,200)* |
a
*, P = 0.001 compared to the PBS and adjuvant control groups; †, P = 0.004 compared to the PBS control group; ‡, P = 0.024 compared to the adjuvant control group.