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Effects of NRTI exposures on HepG2 cell numbers. Cell cultures were exposed to different concentrations of the NRTIs listed, and cell numbers were determined after 6, 9, or 12 days. Data represent the percentage of the numbers for the 0.1% DMSO-treated control cultures and are the means plus SDs (error bars) of three independent experiments. The durations of culture were 6 days, 9 days, and 12 days. **, P < 0.001 by Dunnett's multiple-comparison test.
