TABLE 3.
Activities of ACHN-490 against 461 AG-S and AG-R isolates
| Species | AG susceptibility (n) | No. of isolates with indicated MIC (μg/ml) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | >64 | ||
| Citrobacter spp. | S (15) | 3 | 10 | 2 | |||||||
| R (9) | 3 | 5 | 1 | ||||||||
| Escherichia coli | S (15) | 1 | 5 | 6 | 3 | ||||||
| R (24) | 3 | 14 | 6 | 1 | |||||||
| Enterobacter spp. | S (15) | 2 | 6 | 5 | 1 | 1 | |||||
| R (20) | 2 | 10 | 6 | 1 | 1 | ||||||
| Klebsiella spp. | S (15) | 1 | 12 | 2 | |||||||
| R (45) | 1 | 23 | 18 | 2 | 1 | ||||||
| Proteus mirabilis | S (7) | 3 | 2 | 1 | 1 | ||||||
| R (16) | 1 | 7 | 7 | 1 | |||||||
| Proteae, indole+ | S (23) | 2 | 12 | 7 | 1 | 1 | |||||
| R (8) | 2 | 4 | 2 | ||||||||
| Salmonella and Shigella spp. | S (13) | 1 | 8 | 2 | 2 | ||||||
| R (1) | 1 | ||||||||||
| Serratia spp. | S (20) | 5 | 14 | 1 | |||||||
| R (8) | 2 | 4 | 1 | 1 | |||||||
| Staphylococcus spp. | S (10) | 2 | 5 | 2 | 1 | ||||||
| R (49) | 3 | 21 | 18 | 6 | 1 | ||||||
| Acinetobacter spp. | S (15) | 1 | 3 | 10 | 1 | ||||||
| R (67) | 1 | 2 | 16 | 8 | 19 | 15 | 5 | 1 | |||
| Pseudomonas aeruginosa | S (15) | 3 | 11 | 1 | |||||||
| R (51) | 1 | 3 | 3 | 19 | 10 | 8 | 3 | 4 | |||