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TMC353121 concentrations in plasma, lung tissue, BALF, and ELF of Sprague-Dawley rats and cotton rats at 3 h after a single-bolus i.v. administration of 10 mg/kg
| Rat type | TMC353121 concn (ng/ml)a in: |
|||
|---|---|---|---|---|
| Plasma | Lung tissue | BALF | ELF | |
| Sprague-Dawley | 63 ± 17 | 9,400 ± 1,800 | 11 ± 6 | |
| Cotton | 111 ± 130 | 4,700 ± 1,600 | 23 ± 10 | 392 ± 147 |
Values are mean ± standard deviation (n = 6 animals).
