TABLE 6.
Resistance rates for the most common Gram-negative bacilli isolated from CaNAdian hospitals, based on hospital locationa
| Organism and location (n) | % I/% R |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A/C | CFZ | CPM | CTR | FOX | ETP | MER | PTZ | AMK | GEN | CIP | LEV | MXF | COL | FDb | SXT | TGC | |
| E.coli | |||||||||||||||||
| All (1,132) | 1.4/0.5 | 2.2/10.0 | 1.1/1.6 | 0.9/4.4 | 3.6/5.6 | 0/0 | 0/0 | 1.9/1.2 | 0.2/0.3 | 0.3/9.7 | 0.2/22.1 | 0.5/21.6 | − | − | 1.9/1.1 | 0/27.7 | 0.2/0 |
| Clinic (159) | 2.5/0 | 1.9/6.9 | 0.6/0.6 | 0/2.5 | 3.1/5.0 | 0/0 | 0/0 | 1.9/0.6 | 0/0 | 0.6/8.2 | 0/19.5 | 1.3/18.2 | − | − | 1.3/1.3 | 0/25.8 | 0/0 |
| ER (453) | 0.7/0.7 | 2.2/8.4 | 1.6/1.3 | 0.7/4.0 | 2.4/4.0 | 0/0 | 0/0 | 1.6/0.2 | 0.2/0.2 | 0/9.1 | 0.2/18.5 | 0.4/18.3 | − | − | 2.0/0.4 | 0/27.1 | 0.2/0 |
| ICU (75) | 5.3/0 | 4.0/20.0 | 1.3/2.7 | 4.0/8.0 | 2.7/10.7 | 0/0 | 0/0 | 2.7/4.0 | 0/0 | 1.3/13.3 | 0/28.0 | 1.3/26.7 | − | − | 2.7/1.3 | 0/28.0 | 0/0 |
| Medical (375) | 1.3/0.8 | 1.6/12.0 | 1.1/2.1 | 0.8/5.3 | 4.8/6.9 | 0/0 | 0/0 | 2.4/2.4 | 0.3/0.5 | 0.5/10.4 | 0.3/25.3 | 0.3/25.1 | − | − | 1.6/1.6 | 0/30.1 | 0.3/0 |
| Surgical (70) | 0/0 | 4.3/5.7 | 0/1.4 | 1.4/2.9 | 7.1/5.7 | 0/0 | 0/0 | 1.4/0 | 0/1.4 | 0/10.0 | 0/27.1 | 0/27.1 | − | − | 4.3/1.4 | 0/22.9 | 0/0 |
| P. aeruginosa | |||||||||||||||||
| All (373) | − | − | 12.1/7.2 | 45.8/32.7 | − | − | 4.0/5.6 | 0/8.0 | 2.7/3.5 | 16.6/12.3 | 5.6/19.0 | 11.3/24.1 | − | 7.2/0.8 | − | − | − |
| Clinic (88) | − | − | 7.9/11.4 | 43.2/27.3 | − | − | 5.7/1.1 | 0/10.2 | 4.5/9.1 | 14.8/25.0 | 7.9/17.0 | 12.5/20.4 | − | 6.8/2.3 | − | − | − |
| ER (54) | − | − | 13.0/1.8 | 61.1/22.2 | − | − | 1.8/3.7 | 0/1.8 | 3.7/0 | 20.4/7.4 | 3.7/16.7 | 7.4/18.5 | − | 3.7/0 | − | − | − |
| ICU (67) | − | − | 13.4/6.0 | 44.8/35.8 | − | − | 6.0/9.0 | 0/7.5 | 3.0/6.0 | 14.9/10.4 | 4.5/19.4 | 13.4/25.4 | − | 13.4/0 | − | − | − |
| Medical (131) | − | − | 15.3/6.1 | 44.3/38.2 | − | − | 2.3/5.3 | 0/9.9 | 1.5/0.8 | 16.8/6.1 | 6.9/19.1 | 11.4/25.9 | − | 6.9/0.8 | − | − | − |
| Surgical (33) | − | − | NA | NA | − | − | NA | NA | NA | NA | NA | NA | − | NA | − | − | − |
| K. pneumoniae | |||||||||||||||||
| All (316) | 2.8/0 | 4.8/6.3 | 0.3/0.9 | 1.6/1.3 | 4.1/3.5 | 0/0 | 0/0 | 1.9/2.5 | 0/0.6 | 0.6/2.8 | 2.2/7.3 | 1.3/5.1 | − | − | 31.3/32.6 | 0/11.4 | 3.8/0.6 |
| Clinic (28) | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | − | − | NA | NA | NA |
| ER (80) | 0/0 | 1.2/1.2 | 0/0 | 1.2/0 | 2.5/1.2 | 0/0 | 0/0 | 0/1.2 | 0/0 | 0/1.2 | 2.5/2.5 | 0/0 | − | − | 41.2/25.0 | 0/8.7 | 0/0 |
| ICU (63) | 9.5/0 | 6.3/9.5 | 0/1.6 | 3.2/1.6 | 0/4.8 | 0/0 | 0/0 | 0/6.3 | 0/1.6 | 0/3.2 | 0/3.2 | 0/3.2 | − | − | 25.4/25.4 | 0/6.3 | 3.2/0 |
| Medical (115) | 1.7/0 | 7.8/8.7 | 0.9/1.7 | 0.9/2.6 | 5.2/4.3 | 0/0 | 0/0 | 4.3/2.6 | 0/0.9 | 0.9/4.3 | 1.7/10.4 | 1.7/7.8 | − | − | 29.6/37.4 | 0/15.6 | 6.1/0 |
| Surgical (30) | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | − | − | NA | NA | NA |
a
I, intermediate; R, resistant; NA, no isolates met criteria or there were insufficient numbers for analysis (n < 40); −, no defined breakpoints; A/C, amoxicillin-clavulanate; CFZ, cefazolin; CPM, cefepime; CTR, ceftriaxone; FOX, cefoxitin; ETP, ertapenem; MER, meropenem; PTZ, piperacillin-tazobactam; AMK, amikacin; GEN, gentamicin; CIP, ciprofloxacin; LEV, levofloxacin; MXF, moxifloxacin; COL, colistin; FD, nitrofurantoin; TGC, tigecycline.
b
Indicated for use against urinary tract isolates only (CLSI M100-S19).