Characterisation of Spry3 sequence. (A) Phylogram tree of the Spry family members from Xenopus (Xenopus tropicalis, Xtr), mouse (Mus musculus, Mmu) and zebrafish (Danio rerio, Dre) using ClustalW2. (B) Alignment of the Spry3 protein sequences from Xenopus (Xt), mouse (m) and zebrafish (z). Asterisk, identical residues; colon, conserved residues; dot, semi-conserved residues. The conserved Spry domain is highlighted in yellow.