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PARP processing in wt and bax−/−/bak−/− MEFs treated with SubAB. Cells were treated with either SubAB (100 ng/ml) or SubAA272B (100 ng/ml) for 30 h or 48 h, and lysates were analyzed by Western blotting with anti-PARP antibodies. β-Actin was used as an internal loading control. The mobilities of intact (116-kDa) and cleaved (89-kDa) PARP are indicated. Data are representative of those from two independent experiments.
