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. 2010 Aug 23;78(11):4488–4499. doi: 10.1128/IAI.00620-10

TABLE 1.

Gb4 synthase RNAi knockdown HCT-8 cell line is sensitized to Stx1 and Stx2

Cell linea CD50b (pg)
Stx1 Stx2
Vero 18 35
HCT-8 80 480
HCT-8 scr. 60 1,000
HCT-8 ↓ 1 48
a

HCT-8 scr., scrambled shRNA-containing cells; HCT-8↓, Gb4 synthase-reduced cells.

b

CD50, dose required to kill 50% of the cell monolayer.