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LPA does not stimulate NHE3 activity in Caco-2 cells. Na+/H+ exchange by NHE3 in (A) Caco-2 and (B) C2b/hNHE3V cells was determined in the presence of 50 μM HOE694. NHE3 activity was represented as the rate of Na+-dependent pH recovery, ΔpH/min. n = 8.
