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. Author manuscript; available in PMC: 2010 Nov 9.
Published in final edited form as: Nat Methods. 2008 Dec 7;6(1):91–97. doi: 10.1038/nmeth.1281

Figure 5.

Figure 5

Application of the integrated confidence score. (a) Application of the confidence scoring scheme to the Y2H-positive hsPRS-v1 to exemplify the process. Probabilities for pairs within each assay (middle panel) are computed using LOO-CV and a single-assay logistic regression model, trained identically to the combined-assay regression model. (b) Every reported interaction reported in future protein-protein interaction mapping experiments can be assigned a confidence score based on the tool-kit assay data for each individual protein pair.

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