Table 3. Superiority of the F3 over the NH36 vaccine.

Variable	F3	NH36	Enrichment
IDR 24 h after immunization	0.262	0.178	32.06%
IDR 48 h after immunization	0.173	0.114	34.10%
IDR 48 h after challenge	0.243	0.191	21.40%
Ratio IFN-γ/IL-10 CD4 T cells	1.23	0.77	37.39%
Reduction of parasite load (in vivo depletion)	90.5	65.90	27.18%
Reduction of parasite load L chagasi	88.23	37.06	57.99%
Reduction of parasite load L. amazonensis	100	53.00	47.00%
Mean + SD			36.73+12.33%

Calculation was performed according the following equation  =  (F3-NH36/F3) values x 100 =  protective effect increment.