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Total lung tissue colony forming unit (CFU) counts in infected mice pre-treated with; i) 2× intranasal doses of sterile PBS, and ii) 2× intranasal doses of 500 μg ultrafine-carbon black (UF-CB). At 24 h post-instillation of S pneumonaie, there is a significant decrease in UF-CB treated animals. Data are described by mean ± SEM, n = 5 for each time point for each group. * P < 0.01 by unpaired t test.
