Table 2.
Mean (SD) respiratory chain enzymes activities (expressed as nmol/min/mg protein) in skin fibroblast cultures of patients with Parkinson's disease (PD) and controls (CS = citrate synthase).
| VARIABLE | PARKINSON'S DISEASE (n = 20) | CONTROLS (n = 19) | p values |
|---|---|---|---|
| COMPLEX I/CS | 34.56 (17.10) | 26.13 (9.49) | n.s. |
| COMPLEX II/CS | 19.02 (3.22) | 17.10 (2.77) | n.s. |
| SDH/CS | 14.45 (2.83) | 12.71(3.35) | n.s |
| COMPLEX III/CS | 26.80 (7.97) | 26.75 (5.86) | n.s. |
| COMPLEX IV/CS | 65.70 (10.83) | 62.01 (9.61) | n.s. |
| COMPLEX V/CS | 41.57 (16.70) | 52.52 (23.56) | 0.021 |
| COMPLEX I + III/CS | 380.70 (88.90) | 337.91 (58.85) | n.s. |
| COMPLEX II + III/CS | 16.67 (5.03) | 12.27 (3.33) | n.s |
| CS/protein | 77.39 (28.59) | 74.27 (20.08) | n.s |
| COMPLEX I/protein | 26.70 (11.13) | 22.48 (9.96) | n.s. |
| COMPLEX II/protein | 13.73 (3.79) | 13.22 (3.70) | n.s. |
| SDH/protein | 10.07 (2.85) | 10.17 (3.70) | n.s. |
| COMPLEX III/protein | 20.82 (9.20) | 20.10 (7.51) | n.s. |
| COMPLEX IV/protein | 44.49 (10.53) | 44.49 (11.42) | n.s. |
| COMPLEX V/protein | 29.95 (14.70) | 42.21 (18.80) | 0.017 |
| COMPLEX I + III/protein | 253.76 (79.91) | 247.25 (51.31) | n.s. |
| COMPLEX II + III/protein | 9.89 (3.11) | 9.48 (4.59) | n.s. |