Table 3.
Mean (SD) superoxide-dismutase (SOD), glutathione-peroxidase (GPx), and catalase activities (expressed as units/mg protein); and concentrations of coenzyme Q10 (expressed in nmol/g protein) in skin fibroblast cultures of patients with Parkinson's disease (PD) and controls (CS = citrate synthase).
| VARIABLE | PARKINSON'S DISEASE(n = 20) | CONTROLS (n = 19) | p values |
|---|---|---|---|
| REDUCED CoQ10/CS | 0.41 (0.16) | 0.34 (0.11) | n.s. |
| OXIDIZED CoQ10/CS | 0.75 (0.26) | 0.63 (0.23) | n.s. |
| TOTAL CoQ10/CS | 1.16 (0.33) | 0.97 (0.25) | n.s. |
| REDUCED CoQ10/protein | 24.50 (7.38) | 24.50 (7.38) | n.s. |
| OXIDIZED CoQ10/protein | 56.49 (25.20) | 47.31 (23.50) | n.s. |
| TOTAL CoQ10/protein | 86.27 (29.07) | 71.86 (26.38) | n.s. |
| OXIDIZED Q10/Reduced Q10 | 0.60 (0.27) | 0.62 (0.27) | n.s. |
| MnSOD/protein | 14.20 (8.84) | 11.76 (7.88) | n.s. |
| CuZnSOD/protein | 8.80 (7.08) | 8.90 (6.87) | n.s. |
| TOTAL SOD/protein | 26.00 (8.58) | 20.72 (11.52) | n.s. |
| GPx/protein | 13.03 (4.96) | 14.45 (6.47) | n.s. |
| CATALASE/protein | 9.71 (5.20) | 7.26 (2.05) | n.s. |