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Molecular alterations. (A10 Gelatin zymography assay showed palliative resection activated MMP2. M, size marker; P, positive control. (A2) The percentage of MMP2 activity was elevated 1.4-fold as compared with control (P < 0.01). (A3) Palliative resection up-regulated the tumor MMP2 level (P < 0.01). (B) Palliative resection down-regulated tumor the TIMP2 level (P < 0.05). (C) Palliative resection up-regulated tumor the VEGF level (P < 0.05). The bars indicate the means ± SD.
