Table 5.
Comparison of imputed and observed SNPs in BCL2L11 and risk of NHL subtypes, Mayo Case-Control Study compared with published results from the pooled NCI-SEER, Connecticut, and NSW NHL Case-Control Studies
| CLL/SLL |
Follicular Lymphoma |
DLBCL |
|||||
|---|---|---|---|---|---|---|---|
| SNP ID† | Major/Minor | Ordinal OR | p-trend | Ordinal OR | p-trend | Ordinal OR | p-trend |
| Mayo Study (imputed results) | |||||||
| rs7567444 | C/T | 0.73 (0.53, 1.01) | 0.059 | 0.87 (0.64, 1.20) | 0.41 | 0.91 (0.61, 1.36) | 0.64 |
| rs3789068 | A/G | 1.56 (1.16, 2.10) | 0.0032 | 1.28 (0.95, 1.72) | 0.10 | 1.05 (0.72, 1.52) | 0.79 |
| rs686952 | C/A | 0.74 (0.52, 1.06) | 0.097 | 0.91 (0.65, 1.29) | 0.60 | 1.01 (0.66, 1.54) | 0.98 |
| rs6760053 | C/G | 1.68 (1.15, 2.46) | 0.0077 | 1.31 (0.89, 1.92) | 0.17 | 1.10 (0.68, 1.79) | 0.69 |
| Pooled Study (observed results) | |||||||
| rs7567444 | C/T | 0.93 (0.74, 1.17) | 0.54 | 0.79 (0.68, 0.91) | 0.0009 | 0.91 (0.79, 1.04) | 0.15 |
| rs3789068 | A/G | 1.03 (0.82, 1.29) | 0.80 | 1.28 (1.12, 1.47) | 0.0004 | 1.10 (0.97, 1.26) | 0.14 |
| rs686952 | C/A | 0.93 (0.72, 1.20) | 0.56 | 0.78 (0.67, 0.92) | 0.0023 | 0.87 (0.75, 1.01) | 0.078 |
| rs6760053 | C/G | 1.00 (0.79, 1.26) | 0.99 | 1.19 (1.03, 1.36) | 0.015 | 1.09 (0.95, 1.24) | 0.22 |