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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Gene Ther. 2010 Aug 5;17(12):1506–1516. doi: 10.1038/gt.2010.103

Figure 6.

Figure 6

Repeated sequential chemovirotherapy leads to complete regression of implanted tumors and long-term survival. (A) Time course of tumor growth in mice treated with different regimens of three therapeutics. Groups of about 12 mice were treated, but fatalities due to repeated injections caused some losses in each group, as detailed in Table I. The schedule of each treatment is indicated below the time axis. C: CPA. MV: measles virus. F: fludarabine. (B) Kaplan-Meier survival curves. Symbols are as in panel A. The defined end point was 1,700 μl tumor volume. After day 52, no mice had to be sacrificed because of excessive tumor volume.