The cannabinoid receptor agonist decreased GABA transmission in a concentration-dependent manner in second-order baroreceptive NTS neurons. A. Example traces of mIPSCs recorded before perfusion (control), during WIN 55212-2 (30 μM) perfusion, and during washout period. B. Cumulative probability of the interevent interval (left) and amplitude (right) before, during, and after WIN 55212-2 perfusion. C, left. Group data showing that WIN 55212-2 decreased mIPSC frequency in a concentration-dependent manner (p<0.05, one-way ANOVA). C, right. Group data showing that WIN 55212-2 had no consistent effect on mIPSC amplitude. Numbers in parentheses indicate number of neurons.