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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Eur J Immunol. 2010 Sep 24;40(11):3226–3234. doi: 10.1002/eji.201040349

Figure 6. Negative selection mediated by endogenous superantigen is normal in KSR1−/− DBA1 mice.

Figure 6

KSR1 DBA1/LacJ wild-type or knockout splenocytes were counted and stained with antibodies to CD3, CD4, CD8 and the indicated Vβ TCR antibodies. Data was collected using a BD FACSCalibur and analyzed with Flowjo software. Representative histograms indicating the percentage of Vβ positive cells in T cells from C57BL/6, KSR1 wild-type or knockout splenocytes are shown in A. Cell numbers are shown as percentage of B6 control mouse and are representative of 5 mice per group (B).