Table 3.

The relationships between solar elastosis and lifetime cumulative sun exposure measures in participants in the GEM study (N = 2,304).

Cumulative sun exposure	Solar elastosis		Present vs. absent solar elastosis
			adjusted for pigmentary characteristics & nevi
	Absent	Present	no	yes
	N = 697	N =1,607	OR* (95% CI)	OR† (95% CI)
Site specific measurement§
Site-specific sun exposure hours
Quartile 1	262	302	1.00	1.00
Quartile 2	215	365	1.66 (1.24-2.21)	1.80 (1.34-2.41)
Quartile 3	171	406	1.69 (1.24-2.31)	1.86 (1.35-2.56)
Quartile 4	49	534	4.33 (2.87-6.53)	5.12 (3.35-7.83)
P for trend			< 0.001	< 0.001
Site-specific beach and water UVE dose
None	258	464	1.00	1.00
Tertile 1	208	328	1.24 (0.93-1.66)	1.32 (0.99-1.78)
Tertile 2	138	393	1.66 (1.23-2.26)	1.85 (1.35-2.53)
Tertile 3	104	443	2.06 (1.50-2.83)	2.37 (1.70-3.30)
P for trend			<0.001	<0.001
Site-specific UVE dose
Quartile 1	265	292	1.00	1.00
Quartile 2	232	348	1.53 (1.15-2.04)	1.66 (1.24-2.23)
Quartile 3	154	427	1.91 (1.40-2.61)	2.11 (1.53-2.91)
Quartile 4	46	540	4.41 (2.91-6.69)	5.20 (3.40-7.96)
P for trend			< 0.001	< 0.001
Non-site specific measurement
Total sun exposure hours
Quartile 1	276	284	1.00	1.00
Quartile 2	187	386	1.41 (1.05-1.88)	1.47 (1.10-1.98)
Quartile 3	143	456	1.66 (1.20-2.29)	1.75 (1.26-2.43)
Quartile 4	91	481	1.96 (1.34-2.86)	2.13 (1.45-3.12)
P for trend			< 0.001	< 0.001
Ambient UVE
Quartile 1	322	235	1.00	1.00
Quartile 2	186	365	1.05 (0.72-1.54)	1.07 (0.73-1.58)
Quartile 3	120	471	1.12 (0.65-1.93)	1.16 (0.67-2.01)
Quartile 4	69	536	1.23 (0.59-2.55)	1.29 (0.61-2.70)
P for trend			0.56	0.49

^*Adjusted for age (continuous) sex, and center.

^†Adjusted for age (continuous), sex, center, pigmentary characteristics (hair, eye and skin color, ability to tan, propensity to burn), and back nevi.

^§Site-specific sun exposure measures also adjusted for body site of melanoma